Annual report pursuant to Section 13 and 15(d)

Stockholders' Equity (Deficit) (Details Textual)

Stockholders' Equity (Deficit) (Details Textual) (USD $)	1 Months Ended	12 Months Ended			3 Months Ended	1 Months Ended	2 Months Ended	1 Months Ended
	Oct. 31, 2014	Dec. 31, 2014	Dec. 31, 2013	Dec. 31, 2012	Mar. 31, 2013	Mar. 15, 2011	Mar. 31, 2013	Oct. 31, 2012	Sep. 30, 2012	Apr. 30, 2013	Nov. 30, 2013	Apr. 30, 2012	Apr. 09, 2012
Class of Warrant or Right [Line Items]
Proceeds from Warrant Exercises		$ 0us-gaap_ProceedsFromWarrantExercises	$ 1,275,000us-gaap_ProceedsFromWarrantExercises	$ 4,897,000us-gaap_ProceedsFromWarrantExercises
Underwritten Public Offering, Number of Units Issued	21,000,000
Underwritten Public Offering, Offering Price of Units Issued	$ 0.50
Underwritten Public Offering, Description of Units Issued	each unit consisting of one share of common stock and 0.75 of a warrant, each full warrant to purchase one share of common stock at an exercise price of $0.60 per share.
Underwritten Public Offering, Proceeds from Units Issued	9,600,000
Proceeds from Issuance of Private Placement		9,591,000	4,925,000	7,516,000
Series A Warrants [Member]
Class of Warrant or Right [Line Items]
Class of Warrant or Right Exercised During Period			1,109,010		1,109,010
Proceeds from Warrant Exercises			1,275,000		1,275,000
Deerfield Warrant [Member]
Class of Warrant or Right [Line Items]
Class of Warrant or Right Exercised During Period							6,000,000
Debt Instrument, Increase (Decrease), Net, Total							7,500,000
Class of Warrant or Right, Exercise Price of Warrants or Rights						$ 1.57						$ 1.25
Warrants To Purchase Common Stock Shares						6,000,000
Series A And Series B Warrants [Member]
Class of Warrant or Right [Line Items]
Warrants Not Settleable in Cash, Fair Value Disclosure												2,900,000
Class A Warrant [Member]
Class of Warrant or Right [Line Items]
Underwritten Public Offering, Number of Units Issued	21,000,000
Underwritten Public Offering, Offering Price of Units Issued	$ 0.50
Class of Warrant or Right, Exercise Price of Warrants or Rights	$ 0.60
Warrants To Purchase Common Stock Shares	15,750,000
Series B Warrants [Member]
Class of Warrant or Right [Line Items]
Class of Warrant or Right Exercised During Period				5,761,765				4,627,941	1,133,824
Proceeds from Warrant Exercises								3,934,000	964,000
Class of Warrant or Right, Exercise Price of Warrants or Rights				$ 0.85
Former Lender [Member]
Class of Warrant or Right [Line Items]
Conversion of Stock, Shares Issued										144,499
Class of Warrant or Right Exercised During Period										287,356
Stock Purchase And Option Agreement With Affiliate [Member]
Class of Warrant or Right [Line Items]
Stock Issued During Period, Shares, New Issues									3,400,000		6,250,000
Proceeds from Issuance of Common Stock									4,250,000		5,000,000
Sale of Stock, Price Per Share									$ 1.25		$ 0.80
Stock Purchase And Option Agreement With Affiliate [Member] \| License Revenue [Member]
Class of Warrant or Right [Line Items]
Premium Allocated To Fair Value Option Agreement				1,700,000
Premium Per Share Under Option Agreement				$ 0.50
Common Stock [Member]
Class of Warrant or Right [Line Items]
Stock Issued During Period, Shares, New Issues		21,000,000	6,250,000	9,917,000
Institutional Investor [Member]
Class of Warrant or Right [Line Items]
Proceeds from Issuance of Private Placement												5,540,000
Payments of Stock Issuance Costs												$ 500,000
Institutional Investor [Member] \| Series A Warrants [Member]
Class of Warrant or Right [Line Items]
Class of Warrant or Right, Exercise Price of Warrants or Rights													$ 1.15
Warrants To Purchase Common Stock Shares												6,517,648
Institutional Investor [Member] \| Series B Warrants [Member]
Class of Warrant or Right [Line Items]
Class of Warrant or Right, Exercise Price of Warrants or Rights													$ 0.85
Warrants To Purchase Common Stock Shares												6,517,648
Institutional Investor [Member] \| Common Stock [Member]
Class of Warrant or Right [Line Items]
Stock Issued During Period Shares Private Placement												6,517,648