Annual report pursuant to Section 13 and 15(d)

STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME (LOSS)

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STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME (LOSS) (USD $)
In Thousands, except Per Share data, unless otherwise specified
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Revenue:      
License revenue $ 3,646us-gaap_LicensesRevenue $ 9,057us-gaap_LicensesRevenue $ 2,325us-gaap_LicensesRevenue
Royalty revenue 0us-gaap_RoyaltyRevenue 1,424us-gaap_RoyaltyRevenue 4,750us-gaap_RoyaltyRevenue
Grant revenue 0us-gaap_RevenueFromGrants 0us-gaap_RevenueFromGrants 42us-gaap_RevenueFromGrants
Total revenue 3,646us-gaap_Revenues 10,481us-gaap_Revenues 7,117us-gaap_Revenues
Operating expenses:      
Research and development 4,075us-gaap_ResearchAndDevelopmentExpense 8,309us-gaap_ResearchAndDevelopmentExpense 10,610us-gaap_ResearchAndDevelopmentExpense
General and administrative 3,046us-gaap_GeneralAndAdministrativeExpense 3,063us-gaap_GeneralAndAdministrativeExpense 4,877us-gaap_GeneralAndAdministrativeExpense
Total operating expenses 7,121us-gaap_OperatingExpenses 11,372us-gaap_OperatingExpenses 15,487us-gaap_OperatingExpenses
Loss from operations (3,475)us-gaap_OperatingIncomeLoss (891)us-gaap_OperatingIncomeLoss (8,370)us-gaap_OperatingIncomeLoss
Other income (expense):      
Interest expense, net 0us-gaap_InterestIncomeExpenseNonoperatingNet (1,568)us-gaap_InterestIncomeExpenseNonoperatingNet (4,861)us-gaap_InterestIncomeExpenseNonoperatingNet
Other income (expense), net (11)us-gaap_OtherNonoperatingIncomeExpense 10,433us-gaap_OtherNonoperatingIncomeExpense (183)us-gaap_OtherNonoperatingIncomeExpense
Non-cash gain (loss) on changes in the fair value of warrants 1,083us-gaap_FairValueAdjustmentOfWarrants 1,737us-gaap_FairValueAdjustmentOfWarrants (1,766)us-gaap_FairValueAdjustmentOfWarrants
Other income (expense), net 1,072us-gaap_NonoperatingIncomeExpense 10,602us-gaap_NonoperatingIncomeExpense (6,810)us-gaap_NonoperatingIncomeExpense
Net income (loss) and comprehensive income (loss) applicable to common stockholders $ (2,403)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic $ 9,711us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic $ (15,180)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic
Basic net income (loss) per common share (in dollars per share) $ (0.03)us-gaap_EarningsPerShareBasic $ 0.12us-gaap_EarningsPerShareBasic $ (0.23)us-gaap_EarningsPerShareBasic
Diluted net income (loss) per common share (in dollars per share) $ (0.04)us-gaap_EarningsPerShareDiluted $ 0.10us-gaap_EarningsPerShareDiluted $ (0.23)us-gaap_EarningsPerShareDiluted
Weighted average shares used in computing basic net income (loss) per common share (in shares) 93,814us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 82,099us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 66,509us-gaap_WeightedAverageNumberOfSharesOutstandingBasic
Weighted average shares used in computing diluted net income (loss) per common share (in shares) 93,832us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 82,659us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 66,509us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding