Annual report pursuant to Section 13 and 15(d)

Stockholders' Equity (Deficit)

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Stockholders' Equity (Deficit)
12 Months Ended
Dec. 31, 2014
Stockholders' Deficit [Abstract]  
Stockholders Equity Note Disclosure [Text Block]
11. Stockholders’ Equity (Deficit)
 
Common Stock
 
In October 2014, we completed an underwritten public offering of 21,000,000 units at an offering price of $0.50 per unit, with each unit consisting of one share of common stock and 0.75 of a warrant, each full warrant to purchase one share of common stock at an exercise price of $0.60 per share. Net proceeds were approximately $9.6 million after deducting underwriting discounts, commissions and other related expenses. As a result of the public offering, and pursuant to the terms of the existing Series A Warrants, the exercise price of the Series A Warrants (See Note 9, “Warrant Liability” for further discussion) was adjusted to $0.89 per share.
 
In November 2013, we entered into a stock purchase agreement with Braeburn pursuant to which we sold 6,250,000 shares of our common stock for an aggregate purchase price of $5.0 million, or $0.80 per share.
 
In April 2013, 144,499 shares of common stock were issued to a former lender upon the cashless net exercise of 287,356 warrants in accordance with the terms of the warrants.
 
In January and March 2013, Series A Warrants to purchase 1,109,010 shares of common stock were exercised resulting in gross proceeds of approximately $1,275,000.
 
On February 6, 2013, the facility agreement with Deerfield was amended to provide that the exercise price of the Deerfield Warrants could be satisfied through a reduction in the principal amount of our outstanding indebtedness to Deerfield. In February and March 2013, Deerfield exercised the 6,000,000 Deerfield Warrants resulting in a $7.5 million reduction in the amount owed to Deerfield.
 
In October 2012, Series B Warrants to purchase 4,627,941 shares of common stock were exercised resulting in gross proceeds of approximately $3,934,000.
 
In September 2012, Series B Warrants to purchase 1,133,824 shares of common stock were exercised resulting in gross proceeds of approximately $964,000.
 
In September 2012, we entered into a stock purchase and option agreement with an affiliate of Braeburn pursuant to which we sold 3,400,000 shares of our common stock for an aggregate purchase price of $4.25 million, or $1.25 per share, and agreed to an exclusive option period for execution of the proposed license agreement. The $1.7 million premium, or $0.50 per share, has been allocated to the fair value of the option agreement and was recorded as license revenue in 2012.
   
In April 2012, we entered into subscription agreements with certain institutional investors for the purchase and sale, in a registered direct offering, of (i)  6,517,648 shares of our common stock, (ii)  6,517,648 Series A Warrants and (iii)  6,517,648 Series B Warrants for gross proceeds of $5,540,000 (the “Offering”). As a result of the Offering, and pursuant to the terms of the Deerfield Warrants, the exercise price of the Deerfield Warrants (See Note 9, “Warrant Liability” for further discussion) was adjusted to $1.25 per share.
 
We recorded the gross proceeds from the Offering, net of (i) issuance costs of $0.5 million and (ii) the fair value of the Warrants of $2.9 million (see Note 9, “Warrant Liability”), as common stock paid-in in the Balance Sheets.
 
As of December 31, 2014, warrants to purchase shares of common stock consisted of the following (in thousands, except per share price):
 
 
 
 
 
 
 
 
Outstanding at
 
Date Issued
 
Expiration Date
 
Exercise Price
 
December 31, 2014
 
04/13/2012
 
04/13/2018
 
$
0.89
 
 
5,409
 
10/08/2014
 
10/08/2019
 
$
0.60
 
 
630
 
10/08/2014
 
10/08/2020
 
$
0.60
 
 
15,750
 
 
 
 
 
 
 
 
 
21,789
 
 
Shares Reserved for Future Issuance
 
As of December 31, 2014, shares of common stock reserved by us for future issuance consisted of the following (in thousands):
 
Stock options outstanding
 
 
6,979
 
Shares issuable upon the exercise of warrants
 
 
5,409
 
 
 
 
12,388