Annual report pursuant to Section 13 and 15(d)

Warrant Liability (Details Textual)

v3.3.1.900
Warrant Liability (Details Textual) - USD ($)
 1 Months Ended 2 Months Ended 3 Months Ended 12 Months Ended
Apr. 09, 2012
Mar. 15, 2011
Oct. 31, 2014
Mar. 31, 2013
Mar. 31, 2013
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Apr. 30, 2012
Class of Warrant or Right [Line Items]                    
Proceeds from Warrant Exercises           $ 0 $ 0 $ 1,275,000    
Notional Liquidation Damages           $ 2,500,000        
Underwritten Public Offering, Description of Units Issued     consisting of one share of common stock and 0.75 of a warrant (Class A Warrant).              
Institutional Investor [Member] | Common Stock [Member]                    
Class of Warrant or Right [Line Items]                    
Stock Issued During Period Shares Private Placement 1,185,034                  
Series A Warrants [Member]                    
Class of Warrant or Right [Line Items]                    
Class of Warrant or Right, Exercise Price of Warrants or Rights     $ 4.89              
Class of Warrant or Right Exercised During Period               201,639    
Proceeds from Warrant Exercises               $ 1,275,000    
Class Of Warrant Or Right Subject To Expiry               983,395    
Investment Warrants Expiration Date               Apr. 30, 2018    
Series A Warrants [Member] | Minimum [Member]                    
Class of Warrant or Right [Line Items]                    
Class of Warrant or Right, Exercise Price of Warrants or Rights $ 4.89                  
Series A Warrants [Member] | Maximum [Member]                    
Class of Warrant or Right [Line Items]                    
Class of Warrant or Right, Exercise Price of Warrants or Rights $ 6.32                  
Series A Warrants [Member] | Institutional Investor [Member]                    
Class of Warrant or Right [Line Items]                    
Warrants To Purchase Common Stock Shares 1,185,034                  
Class of Warrant or Right, Exercise Price of Warrants or Rights $ 6.32                  
Series B Warrants [Member]                    
Class of Warrant or Right [Line Items]                    
Class of Warrant or Right, Exercise Price of Warrants or Rights                 $ 4.67  
Class of Warrant or Right Exercised During Period                 1,047,609  
Investment Warrants Expiration Date                 Oct. 31, 2012  
Class Of Warrant Or Right Expired During Period                 137,425  
Series B Warrants [Member] | Institutional Investor [Member]                    
Class of Warrant or Right [Line Items]                    
Warrants To Purchase Common Stock Shares 1,185,034                  
Class of Warrant or Right, Exercise Price of Warrants or Rights $ 4.67                  
Deerfield Warrant [Member]                    
Class of Warrant or Right [Line Items]                    
Warrants To Purchase Common Stock Shares   1,090,910                
Class of Warrant or Right, Exercise Price of Warrants or Rights   $ 8.64               $ 6.88
Debt Instrument, Increase (Decrease), Net, Total       $ 7,500,000            
Class of Warrant or Right Exercised During Period       1,090,910            
Class A Warrant [Member]                    
Class of Warrant or Right [Line Items]                    
Warrants To Purchase Common Stock Shares     2,863,643              
Class of Warrant or Right, Exercise Price of Warrants or Rights     $ 3.30              
Class of Warrant or Right Exercised During Period         201,639          
Proceeds from Warrant Exercises         $ 1,275,000          
Underwriter Warrant [Member]                    
Class of Warrant or Right [Line Items]                    
Warrants To Purchase Common Stock Shares           114,546        
Class of Warrant or Right, Exercise Price of Warrants or Rights           $ 3.30