Annual report pursuant to Section 13 and 15(d)

Income Taxes (Tables)

Income Taxes (Tables)

12 Months Ended

Dec. 31, 2015

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

Deferred income taxes reflect the net tax effects of temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes and operating loss and credit carryforwards. Significant components of our deferred tax assets are as follows (in thousands):

	December 31,
	2015		2014
Deferred tax assets:
Net operating loss carryforwards	$	91,365	$	88,086
Research credit carryforwards		13,884		13,645
Other, net		3,417		3,529
Deferred revenue		—		666
Total deferred tax assets		108,666		105,926
Valuation allowance		(108,666)		(105,926)
Net deferred tax assets	$	—	$	—

Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]

The provision for income taxes consists of state minimum taxes due. The effective tax rate of our provision (benefit) for income taxes differs from the federal statutory rate as follows (in thousands):

	Year Ending December 31,
	2015		2014		2013
Computed at 34%	$	(3,840)	$	(839)	$	3,301
State taxes		(268)		592		213
Book gains (losses) not currently benefited		2,740		454		1,656
Other		(20)		235		(476)
Disallowed interest expense		—		—		160
Revaluation of warrant liability		1,534		(346)		(591)
Research and development credits		(146)		(97)		(583)
Non-cash gain from termination of royalty purchase agreement		—		—		(3,047)
Non-cash gain on settlement of long-term debt		—		—		(632)
Total	$	—	$	(1)	$	1