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Stockholders' Equity (Deficit) (Details Textual) (USD $)
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12 Months Ended | 3 Months Ended | 12 Months Ended | 1 Months Ended | 12 Months Ended | 0 Months Ended | 2 Months Ended | 1 Months Ended | 12 Months Ended | 1 Months Ended | 1 Months Ended | 1 Months Ended | ||||||||||||
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Dec. 31, 2013
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Dec. 31, 2012
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Dec. 31, 2011
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Mar. 31, 2013
Series A Warrants [Member]
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Dec. 31, 2013
Series A Warrants [Member]
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Oct. 31, 2012
Series B Warrants [Member]
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Sep. 30, 2012
Series B Warrants [Member]
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Dec. 31, 2012
Series B Warrants [Member]
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Mar. 15, 2011
Deerfield Warrant [Member]
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Mar. 31, 2013
Deerfield Warrant [Member]
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Apr. 30, 2012
Deerfield Warrant [Member]
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Apr. 30, 2012
Series A And Series B Warrants [Member]
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Apr. 30, 2013
Oxford [Member]
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Nov. 30, 2013
Stock Purchase And Option Agreement With Affiliate [Member]
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Sep. 30, 2012
Stock Purchase And Option Agreement With Affiliate [Member]
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Dec. 31, 2012
Stock Purchase And Option Agreement With Affiliate [Member]
License Revenue [Member]
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Dec. 31, 2013
Common Stock [Member]
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Dec. 31, 2012
Common Stock [Member]
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Apr. 30, 2012
Institutional Investor [Member]
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Apr. 30, 2012
Institutional Investor [Member]
Series A Warrants [Member]
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Apr. 09, 2012
Institutional Investor [Member]
Series A Warrants [Member]
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Apr. 30, 2012
Institutional Investor [Member]
Series B Warrants [Member]
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Apr. 09, 2012
Institutional Investor [Member]
Series B Warrants [Member]
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Apr. 30, 2012
Institutional Investor [Member]
Common Stock [Member]
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| Class of Warrant or Right [Line Items] | ||||||||||||||||||||||||
| Stock Issued During Period, Shares, New Issues | 6,250,000 | 3,400,000 | 6,250,000 | 9,917,000 | ||||||||||||||||||||
| Proceeds from Issuance of Common Stock | $ 5,000,000 | $ 4,250,000 | ||||||||||||||||||||||
| Stock Purchase Price Per Share | $ 0.80 | $ 1.25 | ||||||||||||||||||||||
| Conversion of Stock, Shares Issued | 144,499 | |||||||||||||||||||||||
| Class of Warrant or Right Exercised During Period | 1,109,010 | 1,109,010 | 4,627,941 | 1,133,824 | 5,761,765 | 6,000,000 | 287,356 | |||||||||||||||||
| Proceeds from Warrant Exercises | 1,275,000 | 4,897,000 | 0 | 1,275,000 | 1,275,000 | 3,934,000 | 964,000 | |||||||||||||||||
| Debt Instrument, Increase (Decrease), Net, Total | 7,500,000 | |||||||||||||||||||||||
| Premium Allocated to Fair Value Option Agreement | 1,700,000 | |||||||||||||||||||||||
| Stock Issued During Period Shares Private Placement | 6,517,648 | |||||||||||||||||||||||
| Warrants To Purchase Common Stock Shares | 6,000,000 | 6,517,648 | 6,517,648 | |||||||||||||||||||||
| Proceeds from Issuance of Private Placement | 4,925,000 | 7,516,000 | 0 | 5,540,000 | ||||||||||||||||||||
| Class of Warrant or Right, Exercise Price of Warrants or Rights | 0.85 | 1.57 | 1.25 | 1.15 | 0.85 | |||||||||||||||||||
| Payments of Stock Issuance Costs | 500,000 | |||||||||||||||||||||||
| Warrants Not Settleable in Cash, Fair Value Disclosure | $ 2,900,000 | |||||||||||||||||||||||
| Premium Per Share under Option Agreement | $ 0.50 | |||||||||||||||||||||||