Annual report pursuant to Section 13 and 15(d)

Warrant Liability (Details Textual)

v2.4.0.6
Warrant Liability (Details Textual) (USD $)
 12 Months Ended 12 Months Ended 0 Months Ended
Dec. 31, 2012
Apr. 30, 2012
Apr. 09, 2012
Mar. 15, 2011
Sep. 30, 2010
Dec. 31, 2009
Mar. 15, 2013
Series A Warrants [Member]
Mar. 14, 2013
Series A Warrants [Member]
Apr. 09, 2012
Series A Warrants [Member]
Dec. 31, 2012
Series B Warrants [Member]
Oct. 31, 2012
Series B Warrants [Member]
Sep. 30, 2012
Series B Warrants [Member]
Apr. 09, 2012
Series B Warrants [Member]
Mar. 15, 2011
Deerfield Warrant [Member]
Apr. 30, 2012
Deerfield Warrant [Member]
Warrant Liability (Textual) [Abstract]                              
Deerfield six-year warrants to Purchase common stock shares                           6,000,000  
Six-year warrants to purchase shares of common stock                 6,517,648            
Six month warrants to purchase shares of common stock                         6,517,648    
Issuance Costs       1.57 0.87 2.13     1.15       0.85   1.25
Number of common stock             520,776 520,776   5,761,765 4,627,941 1,133,824      
Stock exercised price                   $ 0.85          
Series B Warrants, Expired                   755,883          
Common stock expiration period                   2012-10          
Warrant Liability (Additional Textual) [Abstract]                              
Initial Exercise price of common stock shares $ 1.57                            
Exercisable and expiration date of Deerfield warrant Mar. 15, 2017                            
Purchase and sale of shares of common stock under subscription agreements   6,517,648 6,517,648