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Organization and Summary of Significant Accounting Policies (Details Textual) (USD $)
Share data in Millions, unless otherwise specified |
12 Months Ended | 1 Months Ended | 12 Months Ended | ||||||
|---|---|---|---|---|---|---|---|---|---|
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Dec. 31, 2012
Segment
Policy
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Dec. 31, 2011
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Dec. 31, 2010
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Dec. 31, 2012
Management [Member]
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Dec. 31, 2011
Management [Member]
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Dec. 31, 2010
Management [Member]
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Dec. 31, 2012
Collaborative Arrangement Co-promotion [Member]
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Dec. 31, 2012
Minimum [Member]
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Dec. 31, 2012
Maximum [Member]
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| Organization and Summary of Significant Accounting Policies (Textual) [Abstract] | |||||||||
| Non-refundable up-front payment | $ 15,750,000 | ||||||||
| License and services revenue | 15,000,000 | ||||||||
| Milestone payment | 50,000,000 | ||||||||
| Additional amount received upon achievement of sales milestones | 130,000,000 | ||||||||
| Additional amount in regulatory milestones | 35,000,000 | ||||||||
| Potential milestone payments | 75,000,000 | ||||||||
| Non-cash stock-based compensation expense | 2,581,000 | 1,177,000 | 733,000 | 2,600,000 | 1,200,000 | 700,000 | |||
| Estimated useful lives of assets | 3 years | 5 years | |||||||
| Organization and Summary of Significant Accounting Policies (Additional Textual) [Abstract] | |||||||||
| Number of operating business segments | 1 | ||||||||
| Number of constraints for investment policy | 2 | ||||||||
| Investments with original maturities period | 3 months | ||||||||
| Total options and warrants | 19.7 | 18.6 | 12.1 | ||||||
| Unrealized gains or losses | 0 | 0 | 0 | ||||||
| Comprehensive loss | (15,180,000) | (15,203,000) | (6,834,000) | ||||||
| Non-cash loss on an increase in the fair value | 1,766,000 | (1,862,000) | |||||||
| Non-cash gain on a decrease in the fair value | $ (1,766,000) | $ 1,862,000 | $ 0 | ||||||
| X | ||||||||||
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- Definition
Cash equivalents maximum maturity period. No definition available.
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| X | ||||||||||
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- Definition
Change in fair value of warrants. No definition available.
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| X | ||||||||||
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- Definition
License and services revenue net. No definition available.
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| X | ||||||||||
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- Definition
Maximum amount eligible to be received on achievement of regulatory milestone. No definition available.
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| X | ||||||||||
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- Definition
Maximum amount eligible to be received on achievement of sales milestone. No definition available.
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| X | ||||||||||
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- Definition
Minimum amount allocated to launch commercialize and continue development of specific product. No definition available.
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| X | ||||||||||
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- Definition
The increase (decrease) during the period, which was recognized in earnings, in the unrealized gains or losses on derivative instruments that are not or are no longer designated as hedging instruments. No definition available.
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| X | ||||||||||
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- Definition
Number of constraints for investment policy. No definition available.
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| X | ||||||||||
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- Details
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| X | ||||||||||
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- Details
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| X | ||||||||||
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- Definition
The change in equity [net assets] of a business enterprise during a period from transactions and other events and circumstances from non-owner sources which are attributable to the reporting entity. It includes all changes in equity during a period except those resulting from investments by owners and distributions to owners, but excludes any and all transactions which are directly or indirectly attributable to that ownership interest in subsidiary equity which is not attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
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- Definition
Additional shares included in the calculation of diluted EPS as a result of the potentially dilutive effect of call options and warrants using the treasury stock method. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
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- Definition
Revenue from multiple-deliverable arrangements that include licensing fees and services revenue. Licensing revenue is consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Licensing arrangements include, but are not limited to, rights to use a patent, copyright, technology, manufacturing process, software or trademark. Licensing fees are generally, but not always, fixed as to amount and not dependent upon the revenue generated by the licensing party. An entity may receive licensing fees for licenses that also generate royalty payments to the entity. Services revenue may be derived by providing other, nonspecified, services during the reporting period. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
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- Definition
Number of operating segments. An operating segment is a component of an enterprise: (a) that engages in business activities from which it may earn revenues and incur expenses (including revenues and expenses relating to transactions with other components of the same enterprise), (b) whose operating results are regularly reviewed by the enterprise's chief operating decision maker to make decisions about resources to be allocated to the segment and assess its performance, and (c) for which discrete financial information is available. An operating segment may engage in business activities for which it has yet to earn revenues, for example, start-up operations may be operating segments before earning revenues. No definition available.
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| X | ||||||||||
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- Definition
Net of tax amount of unrealized holding gain (loss) before reclassification adjustments and transfers on available-for-sale securities. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
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- Definition
Useful life of long lived, physical assets used in the normal conduct of business and not intended for resale, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Examples include, but not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment. No definition available.
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| X | ||||||||||
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- Definition
The amount of consideration recognized during the period for the milestone or milestones. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
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- Definition
The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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