Quarterly report pursuant to Section 13 or 15(d)

Stockholders' Equity (Details)

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Stockholders' Equity (Details) - USD ($)
1 Months Ended 3 Months Ended
Mar. 31, 2022
Feb. 28, 2022
Jan. 31, 2022
Aug. 31, 2021
Jan. 31, 2021
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Equity Offering                
Common Stock shares, Outstanding 12,039,421         12,039,421   9,914,158
Stock-based compensation           $ 253,000 $ 248,000  
Proceeds from Warrant Exercises           $ 1,000 $ 0  
JT Pharmaceuticals                
Equity Offering                
Issuance of common stock, net (in shares)     51,021          
Milestone Payment     $ 100,000          
2015 Plan                
Equity Offering                
Number of additional shares authorized         1,000,000      
Common Stock                
Equity Offering                
Issuance of common stock, net (in shares)           1,151,000 2,725,000  
Common Stock | Restricted stock agreement with Maxim Group, LLC                
Equity Offering                
Number of shares agreed to issue       50,000        
Vesting period       12 months        
Stock-based compensation           $ 27,000    
Pre-Funded Warrants [Member]                
Equity Offering                
Number of warrants issued 974,242         974,242    
Proceeds from Warrant Exercises $ 1,000              
February 2022 Offerings                
Equity Offering                
Issuance of common stock, net (in shares)   1,100,000            
Proceeds from sale of common stock   $ 5,000,000.0            
February 2022 Offerings | Pre-Funded Warrants [Member]                
Equity Offering                
Exercise price of warrants (in dollars per share)   $ 0.001            
Number of warrants issued   2,274,242            
February 2022 Offerings | Unregistered prefunded warrants                
Equity Offering                
Exercise price of warrants (in dollars per share)   $ 0.001            
Number of warrants issued   1,289,796            
February 2022 Offerings | Unregistered five year and six month warrants                
Equity Offering                
Exercise price of warrants (in dollars per share)   $ 1.14            
Warrants term   5 years 6 months            
Number of warrants issued   4,664,038            
January 2021 Offering                
Equity Offering                
Issuance of common stock, net (in shares)         2,725,000      
Exercise price of warrants (in dollars per share)         $ 3.55      
Number of warrants issued         2,725,000      
Proceeds from sale of common stock         $ 8,900,000