Quarterly report pursuant to Section 13 or 15(d)

Subsequent Events (Details Textual)

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Subsequent Events (Details Textual) - Subsequent Event [Member]
Aug. 03, 2018
USD ($)
Aug. 07, 2018
shares
Aug. 03, 2018
EUR (€)
Subsequent Event [Line Items]      
Amount Received Under Amendment To Purchase Agreement $ 1,109,000   € 950,000
Convertible Debt $ 642,000   € 550,000
Long-term Purchase Commitment, Milestones On August 3, 2018, we entered into an amendment (the “Amendment”) to the Purchase Agreement with Molteni. Under the Amendment, Molteni made an immediate payment to us of €950,000 (approximately $1,109,000) and has committed to make a convertible loan to us of €550,000 (approximately $642,000) provided we have submitted our response to the 120-day letter from the EMA on or prior to September 14, 2018 in accordance with the Amendment, both in exchange for the elimination of an aggregate of €2.0 million (approximately $2,335,000) of regulatory milestones provided for in the Purchase Agreement that are potentially payable in 2019, at the earliest.    
2015 Omnibus Equity Incentive Plan [Member]      
Subsequent Event [Line Items]      
Common Stock, Shares Authorized   2,500,000  
Maximum [Member] | 2015 Omnibus Equity Incentive Plan [Member]      
Subsequent Event [Line Items]      
Common Stock, Shares Authorized   3,500,000  
Convertible Debt [Member]      
Subsequent Event [Line Items]      
Debt Instrument, Interest Rate Terms In the event the EMA has not granted marketing approval by December 31, 2019, the Convertible Loan will become due and payable, together with accrued interest at the rate of one-month LIBOR (to the extent in excess of 1.10%) plus 9.50% per annum.