Quarterly report pursuant to Section 13 or 15(d)

Organization and Summary of Significant Accounting Policies (Details Textual)

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Organization and Summary of Significant Accounting Policies (Details Textual) (USD $)
3 Months Ended 12 Months Ended
Mar. 31, 2014
Mar. 31, 2013
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2012
Collaborative Arrangement Co-promotion [Member]
Schedule of Organization and Summary of Significant Accounting Policies [Line Items]          
Non-Cash Gain (Loss) on Changes in Fair Value of Warrants $ (864,000) $ (3,045,000)      
Revenue Recognition, Milestone Method, Revenue Recognized         15,000,000
Cash and Cash Equivalents, at Carrying Value $ 10,239,000 $ 17,606,000 $ 11,798,000 $ 18,102,000