| Stockholders’ Equity | 3 Months Ended | ||
|---|---|---|---|
| Mar. 31, 2023 | |||
| Equity [Abstract] | |||
| Stockholders’ Equity | 
 
 
 Our common stock outstanding as of March 31, 2023 and December 31, 2022 was shares. 
 February 2022 Offerings 
 In February 2022, we completed a registered direct offering with an accredited investor pursuant to which we issued an aggregate of shares of our common stock and 2,274,242 pre-funded warrants to purchase shares of our common stock, with an exercise price of $0.001 per share. In a concurrent private placement, we sold unregistered pre-funded warrants to purchase an aggregate of 1,289,796 shares of common stock with an exercise price of $0.001 per share and issued unregistered five year and six month warrants to purchase an aggregate of 4,664,038 shares of common stock with an exercise price of $1.14. The net cash proceeds from these offerings were approximately $5.0 million after deduction of underwriting fees and other offering expenses. 
 Warrant Exercises 
 In March 2022, we received approximately $1,000 from the exercise of 974,242 pre-funded warrants issued in the February 2022 registered direct offering. 
 
 JT Pharma Milestone 
 In January 2022, we entered into an agreement with JT Pharma to clarify certain provisions of the JT Agreement pursuant to which we agreed that the proof-of-concept milestone provided for in the JT Agreement was achieved and made a payment of $100,000 and issued shares of our common stock to JT Pharma. 
 Restricted Shares 
 In August 2021, we agreed to issue shares of our common stock pursuant to a restricted stock agreement with Maxim Partners, LLC in connection with the entry into an amendment to our existing advisory agreement. The shares vested monthly over months. We recorded approximately $ of stock-based compensation expense during the three months ended March 31, 2022. |