Quarterly report pursuant to Section 13 or 15(d)

Stockholders' Equity (Details)

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Stockholders' Equity (Details) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
May 31, 2022
Apr. 30, 2022
Mar. 31, 2022
Feb. 28, 2022
Jan. 31, 2022
Aug. 31, 2021
Jan. 31, 2021
Jun. 30, 2022
Mar. 31, 2022
Mar. 31, 2021
Jun. 30, 2022
Jun. 30, 2021
Dec. 31, 2021
Equity Offering                          
Common Stock shares, Outstanding               14,629,217     14,629,217   9,914,158
Proceeds from Warrant Exercises                     $ 4,000 $ 0  
Stock-based compensation                     497,000 $ 695,000  
JT Pharmaceuticals                          
Equity Offering                          
Issuance of common stock, net (in shares)         51,021                
Milestone Payment         $ 100,000                
2015 Plan                          
Equity Offering                          
Number of additional shares authorized             1,000,000            
Common Stock                          
Equity Offering                          
Issuance of common stock, net (in shares)                 1,151,000 2,725,000      
Common Stock | Restricted stock agreement with Maxim Group, LLC                          
Equity Offering                          
Number of shares agreed to issue           50,000              
Vesting period           12 months              
Stock-based compensation               $ 27,000     $ 54,000    
Pre-Funded Warrants [Member]                          
Equity Offering                          
Number of warrants issued 1,289,796 1,300,000 974,242           974,242        
Proceeds from Warrant Exercises $ 1,290 $ 1,300 $ 1,000                    
February 2022 Offerings                          
Equity Offering                          
Issuance of common stock, net (in shares)       1,100,000                  
Proceeds from sale of common stock       $ 5,000,000.0                  
February 2022 Offerings | Pre-Funded Warrants [Member]                          
Equity Offering                          
Number of warrants issued       2,274,242                  
Exercise price of warrants (in dollars per share)       $ 0.001                  
February 2022 Offerings | Unregistered prefunded warrants                          
Equity Offering                          
Number of warrants issued       1,289,796                  
Exercise price of warrants (in dollars per share)       $ 0.001                  
February 2022 Offerings | Unregistered five year and six month warrants                          
Equity Offering                          
Number of warrants issued       4,664,038                  
Exercise price of warrants (in dollars per share)       $ 1.14                  
February 2022 Offerings | Five year and six month warrants                          
Equity Offering                          
Warrants term       5 years                  
January 2021 Offering                          
Equity Offering                          
Issuance of common stock, net (in shares)             2,725,000            
Number of warrants issued             2,725,000            
Exercise price of warrants (in dollars per share)             $ 3.55            
Proceeds from sale of common stock             $ 8,800,000