Annual report pursuant to Section 13 and 15(d)

Subsequent Events (Details)

v3.22.1
Subsequent Events (Details) - USD ($)
 1 Months Ended 12 Months Ended
Mar. 31, 2022
Feb. 28, 2022
Jan. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Subsequent Event [Line Items]          
Number of warrants issued         1,112,313
Net cash proceeds       $ 5,000,000.0  
Warrant exercises received       $ 0 $ 7,243,000
JT Agreement [Member]          
Subsequent Event [Line Items]          
Payment On Achieving Milestone     $ 100,000    
JT Pharma [Member]          
Subsequent Event [Line Items]          
Issuance of common stock, net (in shares)     51,021    
February 2022 Offerings          
Subsequent Event [Line Items]          
Issuance of common stock, net (in shares)   1,100,000      
Number of warrants issued   2,274,242      
Exercise price of warrants (in dollars per share)   $ 0.001      
Net cash proceeds   $ 5,000,000.0      
Unregistered prefunded warrants          
Subsequent Event [Line Items]          
Issuance of common stock, net (in shares)   1,289,796      
Exercise price of warrants (in dollars per share)   $ 0.001      
Unregistered five year and six month warrants          
Subsequent Event [Line Items]          
Issuance of common stock, net (in shares)   4,664,038      
Exercise price of warrants (in dollars per share)   $ 1.14      
Subsequent Events [Member]          
Subsequent Event [Line Items]          
Number of warrants issued 974,242        
Warrant exercises received $ 1,000