Exhibit 10.33

[Titan Pharmaceuticals, Inc. Logo]
TITAN PHARMACEUTICALS, INC.
400 Oyster Point Blvd., Suite 505
South San Francisco, CA 94080

October 18, 1999

D.H. Blair Investment Banking Corp.
44 Wall Street
New York, NY 10005

    Re: Titan Pharmaceuticals, Inc. ("Titan")

Gentlemen:

    This will confirm D.H. Blair Investment Banking Corp.'s ("D.H. Blair's") agreement with Titan:


    This letter agreement may be executed in counterparts, each of which shall be deemed an original, and all of which together shall constitute one and the same instrument. Signatures transmitted by facsimile shall be given full effect as original signatures.

    Please confirm that the foregoing correctly sets forth our agreement by signing and returning to the undersigned the enclosed duplicate copy of this letter.

    Very truly yours,
 
 
 
 
 
TITAN PHARMACEUTICALS, INC.
 
 
 
 
 
By:
 
/s/ 
LOUIS R. BUCALO   
      Name: Louis R. Bucalo, M.D.
Title: President & CEO
 
 
 
 
 
Accepted and Agreed to as of
the date first above written:
 
 
 
 
 
D.H. BLAIR INVESTMENT BANKING CORP.
 
 
 
 
 
By:
 
/s/ 
MARTIN A. BELL   
      Name: Martin A. Bell
Title: Vice Chairman
 
 
 
 
 
Accepted and Agreed to as of
the date first above written:
 
 
 
 
 
CONTINENTAL STOCK TRANSFER &
  TRUST COMPANY
 
 
 
 
 
By:
 

Name:
Title: