FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  HUCKEL HUBERT E MD
2. Date of Event Requiring Statement (Month/Day/Year)
03/15/2010
3. Issuer Name and Ticker or Trading Symbol
TITAN PHARMACEUTICALS INC [TTNP:PK]
(Last)
(First)
(Middle)
400 OYSTER POINT BLVD., SUITE 505
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

SO. SAN FRANCISCO, CA 94080
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock, $0.001 par value per share 188,400
D
 
Common Stock, $0.001 par value per share 789
I
By Wife

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Option to Purchase Common Stock 08/28/2000 08/28/2010 Common Stock 30,000 $ 43.625 D  
Option to Purchase Common Stock 08/09/2001 08/09/2011 Common Stock 22,500 $ 11.63 D  
Option to Purchase Common Stock 08/10/2001 08/10/2011 Common Stock 15,000 $ 11.5 D  
Option to Purchase Common Stock 06/18/2002 06/18/2012 Common Stock 5,000 $ 3.57 D  
Option to Purchase Common Stock 08/16/2002 08/16/2012 Common Stock 30,000 $ 1.71 D  
Option to Purchase Common Stock 10/31/2003 10/31/2013 Common Stock 15,000 $ 3.29 D  
Option to Purchase Common Stock 09/01/2004 09/01/2014 Common Stock 30,000 $ 2.37 D  
Option to Purchase Common Stock 08/09/2005 08/09/2015 Common Stock 15,000 $ 2.05 D  
Option to Purchase Common Stock 01/03/2006 01/03/2016 Common Stock 10,000 $ 1.4 D  
Option to Purchase Common Stock   (1) 08/29/2016 Common Stock 20,000 $ 2.35 D  
Option to Purchase Common Stock 09/05/2006 09/05/2016 Common Stock 15,000 $ 2.48 D  
Option to Purchase Common Stock 09/24/2007 09/24/2017 Common Stock 15,000 $ 2.04 D  
Option to Purchase Common Stock 05/30/2008 05/30/2018 Common Stock 25,000 $ 1.52 D  
Option to Purchase Common Stock   (2) 05/17/2019 Common Stock 25,000 $ 0.79 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
HUCKEL HUBERT E MD
400 OYSTER POINT BLVD., SUITE 505
SO. SAN FRANCISCO, CA 94080
  X      

Signatures

/s/ Hubert Huckel 03/15/2010
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) These options vest in 48 equal monthly installments beginning on August 29, 2006.
(2) These options vest in 12 equal monthly installments beginning on May 17, 2009.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, See Instruction 6 for procedure.

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