| 
                   Delaware 
                 | 
                
                   0-27436 
                 | 
                
                   94-3171940 
                 | 
              ||
| 
                   (State
                    or Other Jurisdiction of Incorporation) 
                 | 
                
                   (Commission
                    File Number) 
                 | 
                
                   (IRS
                    Employer Identification No.) 
                 | 
              
| 
                     400
                      Oyster Point Blvd., Suite 505, South San Francisco, CA 
                   | 
                  
                     94080 
                   | 
                |||
| 
                     (Address
                      of Principal Executive Offices) 
                   | 
                  
                     (Zip
                      Code) 
                   | 
                |||
| 
                     Registrant’s
                      telephone number, including area code:  
                   | 
                  
                     650-244-4990 
                   | 
                |||
| 
                       (Former
                        Name or Former Address, is Changed Since Last Report) 
                     | 
                    
| o | 
               Written
                communications pursuant to Rule 425 under the Securities Act (17
                CFR
                230.425) 
             | 
          
| o | 
               Soliciting
                material pursuant to Rule 14a-12(b) under the Exchange Act (17 CFR
                240.14a-12(b))  
             | 
          
| o | 
               Pre-commencement
                communications pursuant to Rule 14d-2(b) under the Exchange Act (17
                CFR
                240.14d-2(b))  
             | 
          
| o | 
               Pre-commencement
                communications pursuant to Rule 13e-4(c) under the Exchange Act (17
                CFR
                240.13e-4(c))  
             | 
          
| 
               TITAN
                PHARMACEUTICALS, INC. 
             | 
          ||
|   | 
              | 
              | 
          
| Date: December 27, 2005 | By: | /s/ Robert E. Farrell | 
| 
               Name: Robert E. Farrell  | 
          ||
| 
               Title:
                Chief Financial Officer 
             | 
          ||