Annual report pursuant to Section 13 and 15(d)

Organization and Summary of Significant Accounting Policies (Details Textual)

v2.4.0.6
Organization and Summary of Significant Accounting Policies (Details Textual) (USD $)
Share data in Millions, unless otherwise specified
12 Months Ended 1 Months Ended 12 Months Ended
Dec. 31, 2012
Segment
Policy
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2012
Management [Member]
Dec. 31, 2011
Management [Member]
Dec. 31, 2010
Management [Member]
Dec. 31, 2012
Collaborative Arrangement Co-promotion [Member]
Dec. 31, 2012
Minimum [Member]
Dec. 31, 2012
Maximum [Member]
Organization and Summary of Significant Accounting Policies (Textual) [Abstract]                  
Non-refundable up-front payment             $ 15,750,000    
License and services revenue             15,000,000    
Milestone payment             50,000,000    
Additional amount received upon achievement of sales milestones             130,000,000    
Additional amount in regulatory milestones             35,000,000    
Potential milestone payments             75,000,000    
Non-cash stock-based compensation expense 2,581,000 1,177,000 733,000 2,600,000 1,200,000 700,000      
Estimated useful lives of assets               3 years 5 years
Organization and Summary of Significant Accounting Policies (Additional Textual) [Abstract]                  
Number of operating business segments 1                
Number of constraints for investment policy 2                
Investments with original maturities period 3 months                
Total options and warrants 19.7 18.6 12.1            
Unrealized gains or losses 0 0 0            
Comprehensive loss (15,180,000) (15,203,000) (6,834,000)            
Non-cash loss on an increase in the fair value 1,766,000 (1,862,000)              
Non-cash gain on a decrease in the fair value $ (1,766,000) $ 1,862,000 $ 0